研究队伍
谭海东

籍  贯:山东省济宁。
出生日期:1971年1月28日。
职  称:副研究员, 研究生导师。
方向:分子生物学
通讯地址:中科院大连化学物理研究所1805组
     大连市中山路457号(116023)
电子信箱:hdtan@dicp.ac.cn

1988年7月— 1990年7月 青岛海洋大学海洋生物系
1990年7月— 1994年9月 山东济宁任城一中 生物教学
1994年9月— 1997年7月 东北师范大学遗传与细胞研究所  遗传 读硕士
1997年7月─2002年3月  大连生物技术研究所 基因工程
2002年3 月— 2003年 12 月 重庆雨水集团生物制药研究所 研究人员
2003年12月─2007年9月  大连化物所1816组 助理研究员 分子生物学
2009年8月─ 2011年3月 日本冈山大学 分子生物学 在职博士
2007年10 月— 2011年9月   大连化物所1816组 副研究员 硕士导师
2011年10月-2012年9月 东京大学农学部 特任副教
2012年11月-                大连化物所1805组 副研究员

参与项目
1基于压电效应的NAD+与苹果酸酶非共价相互作用研究(国家自然基金: 21102143)
2木质纤维素资源高效生物降解转化中的关键科学问题研究(973项目:2011CB707405)

专著
Haidong Tan and Masaharu Seno. 2011. Exploring the Mechanism of Biological Evolution: DNA Methyltransferase is the Pushing Power for DNA and Protein Evolution. LAP LAMBERT Academic Publishing. ISBN-10: 3844317252.

代表性文章:
1) Tan, H., Wang, J., Yang, F., and Zhao, Z. (2008) Genome-wide analysis of coding DNA and amino acid variation in S. cerevisiae, Yeast 25, 29-39.
2)Tan, H. (2010) Genome-wide analysis of recombination machinery for spliceosomal introns gain, Molecular Biology Reports 37, 1551-1557.
3) Tan, H., Fu, L., and Seno, M. (2010) Optimization of bacterial plasmid transformation using nanomaterials based on the yoshida effect, International Journal of Molecular Sciences 11, 4962-4972.
4) Tan, H., Li, S., Du, X., and Seno, M. (2010) First report of Cucumber mosaic virus in sweet cherry in the People s Republic of China, Plant Disease 94, 1378.
5) Tan, H., Li, Y., Chen, L., Kasai, T., and Seno, M. (2011) Construction of a high-efficiency multi-site-directed mutagenesis, African Journal of Biotechnology 10, 449-452
6)  Tan, H., Li, Y., Chen, L., Kudoh T., Kasai, T., and Seno, M. (2012) The conformational polymorphism of green fluorescent protein, Molecular Biology, Molecular Biology, 46 (1), 142-148.
7) Tan, H., Dan, G., Gong, H., and Cao, L.(2005) On-column refolding and purification of recombinant human interleukin-1 receptor antagonist (rHuIL-1ra) expressed as inclusion body in Escherichia coli, Biotechnology Letters 27, 1177-1182.
8) Tan, H., Dan, G., Gong, H., and Cao, L.(2005) Purification and characterization of recombinant truncated human interleukin-11 expressed as fusion protein in Escherichia coli, Biotechnology Letters 27, 905-910.
9) Tan, H., Dan, G., Gong, H., and Cao, L. (2005) Purification of recombinant human interleukin-1 receptor antagonist and analysis of its two different oxidative forms, Journal of Harbin Institute of Technology 37, 1599-1602.
10) Tan, H., Chen, Q., Wang, L., Liu, W., and Su, H. (2006) Precise relationship between Chlamys farreri, Mizuhopecten yessoensis inferred from internal transcribed spacers and 5.8 s ribosomal DNA, Electronic Journal of Biology 2, 42-44.
11) Yang, L., Xu, F., Sun, L., Tan, Z., Tan, H., Zhao, Z., and Liang, J. (2006) Study on interaction between antibiotics and Escherichia coli DH5a by microcalorimetric method, Journal of Thermal Analysis and Calorimetry 85, 807-810.
12) Hua, S., Li, S., and Tan, H. (2007) Molecular sequencing and analysis of soluble methane monooxygenase gene clusters from methanotroph Methylomonas sp. GYJ3, World Journal of Microbiology & Biotechnology 23, 323-330.
13) Hua, S., Li, S., Tan, H., and Zhao, J. (2007) Sequence analysis of 16S rDNA and genes of soluble methane monooxygenase from Methylomonas sp. GYJ3, Wei Sheng Wu Xue Bao 47, 150-155.
14) Hua, S., Li, S., Xin, J., Niu, J., Xia, C., Tan, H., and Tang, W. (2007) Purification and biochemical characterization of soluble methane monooxygenase hydroxylase from Methylosinus trichosporium IMV 3011, Bioscience Biotechnology and Biochemistry 71, 122-129.
15) Tan, H., Wang, J., and Zhao, Z.(2007) Purification and refolding optimization of recombinant bovine enterokinase light chain overexpressed in Escherichia coli, Protein Expr Purif 56, 40-47.
16) Wang, J., Tan, H., and Zhao, Z. (2007) Over-expression, purification, and characterization of recombinant NAD-malic enzyme from Escherichia coli K12, Protein Expression and Purification 53, 97-103.
17) Wang, J., Zhang, S., Tan, H., and Zhao, Z.(2007) PCR-based strategy for construction of multi-site-saturation mutagenic expression library, Journal of Microbiological Methods 71, 225-230.
18) Tan, H., Wu, S., Wang, J., and Zhao, Z.(2008) The JMJD2 members of histone demethylase revisited, Molecular Biology Reports 35, 551-556.
19) Tang, W., Zhang, S., Wang, Q., Tan, H., and Zhao, Z. (2009) The isocitrate dehydrogenase gene of oleaginous yeast Lipomyces starkeyi is linked to lipid accumulation, Canadian Journal of Microbiology 55, 1062-1069.
20) Lin, J., Shen, H., Zhang, Z., Hu, C., Jin, G., Tan, H., and Zhao, Z.(2010) Microbial lipid production by Rhodosporidium toruloides in a two-stage culture mode, Sheng Wu Gong Cheng Xue Bao 26, 997-1002.
21) Tan, H., Wang, L., and Zhao, Z.(2010) Mechanism of DNA transformation based on mineral nanofibers and method improvement, Sheng Wu Gong Cheng Xue Bao 26, 1379-1384.
22) Tang, W., Zhang, S., Tan, H., and Zhao, Z. (2010) Molecular cloning and characterization of a malic enzyme gene from the oleaginous yeast Lipomyces starkeyi, Molecular Biotechnology 45, 121-128.
23) Yang, F., Tan, H., Zhou, Y., Lin, X., and Zhang, S. (2011) High-quality RNA preparation from rhodosporidium toruloides and cDNA library construction, Molecular Biotechnology 47, 144-151.
24) Kitagaki, H., Tan, H., and Jayakody, N.(2013) Analysis of the Role of Mitochondria of Sake Yeast during Sake Brewing and Its Applications in Fermentation Technologies. AGri- Bioscience Monographs 3, 1-12. 

 
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